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Halozyme Therapeutics Inc

Recommendation: Buy

Entry Date Symbol Recommendation Entry Price (USD) Target 1 (USD) Target 2 (USD) Holding Duration Position Status Return(%)*
29 Jan, 26 HALO Buy USD 72.83 USD 76.5 USD 81.0 8 days Closed 11.26%

*Return(%) represent the percentage change between the entry price and exit price of the recommendation.

Fundamentals

  • Previous Close 68.57
  • Market Cap8104.83M
  • Volume3654030
  • P/E Ratio26.72
  • Dividend Yield-%
  • EBITDA897.84M
  • Revenue TTM1396.61M
  • Revenue Per Share TTM11.65
  • Gross Profit TTM 1086.35M
  • Diluted EPS TTM2.56

Data Powered by EOD Historical Data (“EODHD”).

Company Overview

Halozyme Therapeutics, Inc., a biopharmaceutical company, researches, develops, and commercializes of proprietary enzymes and devices in the United States, Switzerland, Belgium, Japan, and internationally. The company's products are based on the patented recombinant human hyaluronidase enzyme (rHuPH20) that enables delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. It offers Hylenex recombinant, a formulation of rHuPH20 that facilitates subcutaneous (SC) administration to enhance the dispersion and absorption of other injected drugs in SC urography and to enhance resorption of radiopaque agents; and XYOSTED, an injection for SC administration of testosterone replacement therapy. The company also provides Herceptin (trastuzumab) under the brand name Herceptin Hylecta; and Phesgo to treat breast cancer; Mabthera SC for chronic lymphocytic leukemia treatment; Tecentriq SC for IV infusion; Ocrevus SC for multiple sclerosis; HYQVIA to treat primary immunodeficiency disorders; DARZALEX to treat amyloidosis, and smoldering and multiple myeloma; epinephrine Injection to treat allergic reactions; nivolumab and relatlimab to treat metastatic or unresectable melanoma; teriparatide injections; ARGX-113; and ARGX-117 to treat severe autoimmune diseases in multifocal motor neuropathy. It has collaborations and licensing agreements with F. Hoffmann-La Roche, Ltd. and Hoffmann-La Roche, Inc.; Takeda Pharmaceuticals International AG and Baxalta US Inc.; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol Myers Squibb Company; argenx BVBA; ViiV Healthcare; Chugai Pharmaceutical Co., Ltd.; Acumen Pharmaceuticals, Inc.; Merus N.V.; and Skye Bioscience, Inc. The company was founded in 1998 and is headquartered in San Diego, California.

Key Positives

Significant Operating Leverage and Profit Expansion: Operating income improved markedly from USD 163.2 million in Q3 FY24 to USD 217.9 million in Q3 FY25, translating into a 34% year-over-year increase

Sharp Acceleration in High-Margin Royalty Revenue: During Q3 FY25, Halozyme’s royalty revenue increased from USD 155.1 million in Q3 FY24 to USD 236.0 million, representing a substantial 52% year-over-year growth

Key Negatives

Rising Cost of Sales Pressuring Gross Margins: Cost of sales increased from USD 49.4 million in Q3 FY24 to USD 55.2 million in Q3 FY25, marking a 12% rise year-over-year

Sharp Decline in Collaboration and Milestone Revenue: Revenues under collaborative agreements declined significantly from USD 48.4 million in Q3 FY24 to USD 24.0 million in Q3 FY25, reflecting a 50% year-over-year decrease

Key Investment Risks

Halozyme’s financial performance remains highly dependent on sustained commercial success and regulatory expansion of a concentrated portfolio of ENHANZE®-enabled partner therapies, exposing earnings to partner execution risks, competitive biologic alternatives, and potential patent or reimbursement challenges

Recommendation Summary

Technical Summary

Entry Price Support* Target 1** Target 2**
72.83 65.0 76.5 81.0

Data Source: REFINITIV, Analysis: StockNextt

*Support can be considered as an indicative stop-loss, and if prices move below that level on closing basis individuals may evaluate exiting the position depending on their risk appetite, previous holdings, and other factors considered. The support and resistance levels may need to be re-evaluated within 4-6 weeks’ time frame depending on the stock price movements from the date of recommendation on the stock.

**Target prices may vary by ±0.5% depending on market volatility.

Key Reasons for Buy

Royalty-Led Revenue Expansion Driving Top-Line Momentum: Halozyme delivered a robust revenue performance in Q3 FY25, with total revenue rising to USD 354.3 million from USD 290.1 million in Q3 FY24, reflecting a 22% year-over-year increase, largely fueled by strong royalty inflows from ENHANZE®-enabled therapies. Royalty revenue alone surged 52% to USD 236.0 million, supported by accelerating adoption of blockbuster products such as DARZALEX® SC, Phesgo®, and VYVGART® Hytrulo across global markets.

Sustained Commercial Uptake Across Partner Products: Operational execution remained strong as Halozyme benefited from expanding subcutaneous drug conversions and multiple new regulatory approvals across Europe, the U.S., and Japan. The continued shift from intravenous to subcutaneous delivery for key biologics significantly enhanced partner product penetration, reinforcing the Company’s recurring royalty-driven business model and expanding long-term revenue visibility.

Margin Expansion Through High-Quality Revenue Mix: The sharp growth in high-margin royalty income translated into notable profitability improvements. Operating income increased to USD 217.9 million from USD 163.2 million, representing a 34% year-over-year rise, while adjusted EBITDA expanded 35% to USD 248.2 million, reflecting strong operating leverage and disciplined cost control amid rising revenues.

Improving Bottom-Line Performance and Earnings Strength: Net income advanced to USD 175.2 million in Q3 FY25 from USD 137.0 million in Q3 FY24, marking a 28% increase, driven by revenue scale and stable operating expense growth. GAAP diluted earnings per share rose 36% to USD 1.43, while non-GAAP diluted EPS climbed 35% to USD 1.72, highlighting meaningful shareholder value creation.

Operational Efficiency and Cost Discipline: While total operating expenses increased modestly by 7% year-over-year to USD 136.3 million, the Company achieved efficiency gains through lower research and development spending and controlled amortization expenses. This was partially offset by higher SG&A driven by acquisition-related diligence and litigation costs, yet overall expense growth remained well below revenue growth, reinforcing scalability.

Strengthening Balance Sheet and Cash Generation: Halozyme closed Q3 FY25 with USD 702.0 million in cash and marketable securities, up from USD 596.1 million at year-end FY24, supported by strong operating cash flows despite ongoing share repurchases. This financial flexibility positions the Company to fund strategic acquisitions such as Elektrofi while continuing shareholder returns.

Upward Revision of Full-Year Growth Outlook: Reflecting sustained momentum, Halozyme raised its FY25 guidance, projecting total revenue of USD 1.30–USD 1.38 billion, adjusted EBITDA of USD 885–USD 935 million, and non-GAAP EPS of USD 6.10–USD 6.50, implying continued strong double-digit growth across profitability metrics driven primarily by royalty expansion.

Considering recent key business, financial updates, current trading levels, and key business risks, a ‘Buy’ recommendation has been given to Halozyme Therapeutics, Inc. (NASDAQ: HALO) at the closing market price of USD 72.83, as on Jan 29, 2026

Key Financials in Pictures

Income Statement

Balance Sheet

Change in Cash

Total Operating Cash

Dividends Paid

Data Powered by EOD Historical Data (“EODHD”).

Peer Comparison

Sector: Healthcare Industry: Biotechnology

Company Change (USD) Price (USD) Trailing PE (x) Forward PE (x) Price Sales TTM (x) Price to Book Value (x) Enterprise Value to Revenue (x) Enterprise Value to EBITDA (x)
HALO
Halozyme Therapeutics Inc
-0.02 0.03% 68.55 26.72 5.13 5.80 168.90 7.34 17.88
NVO
Novo Nordisk A/S
-0.33 0.76% 43.19 41.58 31.15 2.13 32.99 2.11 4.70
NONOF
Novo Nordisk A/S
- -% 43.40 41.06 31.25 2.08 33.11 2.11 4.70
VRTX
Vertex Pharmaceuticals Inc
-7.36 1.60% 451.63 29.67 24.33 10.38 5.83 9.33 20.00
REGN
Regeneron Pharmaceuticals Inc
2.01 0.33% 609.94 29.07 20.12 7.57 3.82 6.95 19.42

Data Powered by EOD Historical Data (“EODHD”).

Disclosures:

Markets are trading in a highly volatile zone currently due to certain macro-economic issues and prevailing geopolitical tensions. Therefore, it is prudent to follow a cautious approach while investing.

Related Risks: This report may be looked at from high-risk perspective and recommendations are provided are for a short duration. Recommendations provided in this report are solely based on technical parameters, and the fundamental performance of the stocks has not been considered in the decision-making process. Other factors which could impact the stock prices include market risks, regulatory risks, interest rates risks, currency risks, social and political instability risks etc.

Note 1: Past performance is not a reliable indicator of future performance.

Note 2: The reference date for all price data, currency, technical indicators, support, and resistance levels as on January 29, 2026. The reference data in this report has been partly sourced from REFINITIV.

Note 3: Investment decisions should be made depending on an individual's appetite for upside potential, risks, holding duration, and any previous holdings. An 'Exit' from the stock can be considered if the Target Price mentioned has been achieved and is subject to the factors discussed above.

Note 4: StockNextt reports are prepared based on the stock prices captured either from REFINITIV or Trading View. Typically, REFINITIV or Trading View may reflect stock prices with a delay which could be a lag of 15-20 minutes. There can be no assurance that future results or events will be consistent with the information provided in the report. The information is subject to change without any prior notice.

Technical Indicators Defined: -

Support: A level at which the stock prices tend to find support if they are falling, and a downtrend may take a pause backed by demand or buying interest. Support 1 refers to the nearby support level for the stock and if the price breaches the level, then Support 2 may act as the crucial support level for the stock.
Target: A level at which the stock prices tend to find resistance when they are rising, and an uptrend may take a pause due to profit booking or selling interest. Target 1 refers to the nearby resistance level for the stock and if the price surpasses the level, then Target 2 may act as the crucial resistance level for the stock.
Stop-loss: It is a level to protect further losses in case of unfavourable movement in the stock prices.

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